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The Muscle Chloride Channel ClC-1 Has a Double-Barreled Appearance that Is Differentially Affected in Dominant and Recessive Myotonia

Single-channel recordings of the currents mediated by the muscle Cl(−) channel, ClC-1, expressed in Xenopus oocytes, provide the first direct evidence that this channel has two equidistant open conductance levels like the Torpedo ClC-0 prototype. As for the case of ClC-0, the probabilities and dwell...

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Detalhes bibliográficos
Main Authors: Saviane, Chiara, Conti, Franco, Pusch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222904/
https://ncbi.nlm.nih.gov/pubmed/10051520
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