THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

Cytochromes P450 (P450s) 3A, 2C, and 1A2 constitute the major “pieces” of the human liver P450 “pie” and account, on average, for 40, 25, and 18%, respectively, of total immunoquantified P450s (J Pharmacol Exp Ther 270:414–423, 1994). The P450 profile in the human small intestine has not been fully...

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Main Authors: Paine, Mary F., Hart, Heather L., Ludington, Shana S., Haining, Robert L., Rettie, Allan E., Zeldin, Darryl C.
Format: Artigo
Jezik:Inglês
Izdano: 2006
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222892/
https://ncbi.nlm.nih.gov/pubmed/16467132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.105.008672
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