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Arginine Auxotrophic Phenotype of Mutations in pyrA of Salmonella typhimurium: Role of N-Acetylornithine in the Maturation of Mutant Carbamylphosphate Synthetase

Mutations in pyrA that abolish catalytic activity of carbamylphosphate synthetase cause auxotrophy for both arginine and a pyrimidine. Eight pyrA mutants auxotrophic only for arginine (AUX) were isolated by the mutagenized phage technique; three of these required arginine only at low temperature (20...

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Autori principali: Abdelal, Ahmed T. H., Griego, Elizabeth, Ingraham, John L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1978
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC222283/
https://ncbi.nlm.nih.gov/pubmed/207669
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