Screening for TP53 mutations in patients and tumours from 109 Swedish breast cancer families.

To estimate the prevalence of TP53 mutations in familial breast cancer, constant denaturant gel electrophoresis (CDGE) was used to screen exons 5-8 of the TP53 gene for germline mutations. Genomic DNA from 128 breast cancer patients belonging to 109 families with familial cancer were screened. No ge...

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Detaylı Bibliyografya
Asıl Yazarlar: Zelada-Hedman, M., Børresen-Dale, A. L., Claro, A., Chen, J., Skoog, L., Lindblom, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222784/
https://ncbi.nlm.nih.gov/pubmed/9099970
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