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Enhanced performance in prediction of protein active sites with THEMATICS and support vector machines

Theoretical microscopic titration curves (THEMATICS) is a computational method for the identification of active sites in proteins through deviations in computed titration behavior of ionizable residues. While the sensitivity to catalytic sites is high, the previously reported sensitivity to catalyti...

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Detalhes bibliográficos
Main Authors: Tong, Wenxu, Williams, Ronald J., Wei, Ying, Murga, Leonel F., Ko, Jaeju, Ondrechen, Mary Jo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222725/
https://ncbi.nlm.nih.gov/pubmed/18096640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073213608
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