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Enhanced performance in prediction of protein active sites with THEMATICS and support vector machines
Theoretical microscopic titration curves (THEMATICS) is a computational method for the identification of active sites in proteins through deviations in computed titration behavior of ionizable residues. While the sensitivity to catalytic sites is high, the previously reported sensitivity to catalyti...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2222725/ https://ncbi.nlm.nih.gov/pubmed/18096640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073213608 |
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