Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus

The non-structural protein Nsp15 from the aetiological agent of SARS (severe acute respiratory syndrome) has recently been characterized as a uridine-specific endoribonuclease. This enzyme plays an essential role in viral replication and transcription since a mutation in the related H229E human coro...

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Hauptverfasser: Ricagno, Stéfano, Coutard, Bruno, Grisel, Sacha, Brémond, Nicolas, Dalle, Karen, Tocque, Fabienne, Campanacci, Valérie, Lichière, Julie, Lantez, Violaine, Debarnot, Claire, Cambillau, Christian, Canard, Bruno, Egloff, Marie-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2006
Schlagworte:
Crystallization Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222560/
https://ncbi.nlm.nih.gov/pubmed/16582498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106009407
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