Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo (13)C NMR

Recent (13)C NMR studies in rat models have shown that the glutamate/glutamine cycle is highly active in the cerebral cortex and is coupled to incremental glucose oxidation in an ≈1:1 stoichiometry. To determine whether a high level of glutamatergic activity is present in human cortex, the rates of...

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Detalhes bibliográficos
Main Authors: Shen, Jun, Petersen, Kitt F., Behar, Kevin L., Brown, Peter, Nixon, Terrence W., Mason, Graeme F., Petroff, Ognen A. C., Shulman, Gerald I., Shulman, Robert G., Rothman, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22218/
https://ncbi.nlm.nih.gov/pubmed/10393978
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