ロード中...

Genetic and Chemical Modifiers of a CUG Toxicity Model in Drosophila

Non-coding CUG repeat expansions interfere with the activity of human Muscleblind-like (MBNL) proteins contributing to myotonic dystrophy 1 (DM1). To understand this toxic RNA gain-of-function mechanism we developed a Drosophila model expressing 60 pure and 480 interrupted CUG repeats in the context...

詳細記述

保存先:
書誌詳細
主要な著者: Garcia-Lopez, Amparo, Monferrer, Lidon, Garcia-Alcover, Irma, Vicente-Crespo, Marta, Alvarez-Abril, M. Carmen, Artero, Ruben D.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2220037/
https://ncbi.nlm.nih.gov/pubmed/18270582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001595
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!