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Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin

The hematopoietic stem cell (HSC) is defined as a cell that can either self-replicate or generate daughter cells that are destined to commit to mature cells of different specific lineages. Self-replication of the most primitive HSC produces daughter cells that possess a long (possibly unlimited) clo...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yagi, Mayumi, Ritchie, Kindred A., Sitnicka, Ewa, Storey, Carl, Roth, Gerald J., Bartelmez, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.8126
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