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Molecular Crowding Inhibits Intramolecular Breathing Motions in Proteins
In aqueous solution some proteins undergo large-scale movements of secondary structures, subunits or domains - referred to as protein ‘breathing’ - that define a native-state ensemble of structures. These fluctuations are sensitive to the nature and concentration of solutes and other proteins and ar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2219890/ https://ncbi.nlm.nih.gov/pubmed/18031757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.075 |
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