The Signaling Pathway Involved in Neutrophil Elastase–Stimulated MUC1 Transcription

We previously reported that neutrophil elastase (NE) stimulated MUC1 gene expression in A549 lung epithelial cells through binding of Sp1 to the MUC1 promoter element. The current study was undertaken to elucidate the complete signaling pathway leading to Sp1 activation. Using a combination of pharm...

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Bibliographic Details
Main Authors: Kuwahara, Ippei, Lillehoj, Erik P., Koga, Takeshi, Isohama, Yoichiro, Miyata, Takeshi, Kim, K. Chul
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219551/
https://ncbi.nlm.nih.gov/pubmed/17600314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0072OC
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