Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis

The intracellular pathogens Propionibacterium acnes and Mycobacterium tuberculosis have been leading suspects as the cause of sarcoidosis, a systemic disorder characterized by the formation of non-caseating granulomas. Toll-like receptor (TLR) 2 is important in the innate immune response against bot...

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Detalhes bibliográficos
Main Authors: Veltkamp, M, Wijnen, P A H M, van Moorsel, C H M, Rijkers, G T, Ruven, H J T, Heron, M, Bekers, O, Claessen, A M E, Drent, M, van den Bosch, J M M, Grutters, J C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219322/
https://ncbi.nlm.nih.gov/pubmed/17565608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03428.x
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