Amelioration of lacrimal gland inflammation by oral administration of K-13182 in Sjögren's syndrome model mice

Regulation of the adhesion of mononuclear cells to endothelial cells is considered to be a critical step for the treatment of inflammatory diseases, including autoimmune diseases. K-13182 was identified as a novel inhibitor for these adhesions. K-13182 inhibited the expression of vascular cell adhes...

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Bibliographic Details
Main Authors: Nishiyama, T, Mishima, K, Obara, K, Inoue, H, Doi, T, Kondo, S, Saka, M, Tabunoki, Y, Hattori, Y, Kodama, T, Tsubota, K, Saito, I
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Translational Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219315/
https://ncbi.nlm.nih.gov/pubmed/17614971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03448.x
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