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Inhibition of Thromboxane A Synthase Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells

The cyclooxygenase-2 (COX2)-dependent inhibition of Leydig cell steroidogenesis has been demonstrated. To understand the mechanism for this effect of COX2, the present study examined the role of an enzyme downstream of COX2, namely thromboxane A synthase (TBXAS), in steroidogenesis. Inhibition of TB...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wang, XingJia, Yin, Xiangling, Schiffer, Randolph B., King, Steven R., Stocco, Douglas M., Grammas, Paula
פורמט: Artigo
שפה:Inglês
יצא לאור: The Endocrine Society 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219308/
https://ncbi.nlm.nih.gov/pubmed/18006634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0470
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