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Exon shuffling mimicked in cell culture

Undesired side products of DNA transfections are usually discarded. However, here, we show that such products may provide insight into mutational events that are also a major driving force in protein evolution. While studying the small heat-shock protein αA-crystallin, we transfected the hamster αA-...

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Autori principali: van Rijk, Anke A. F., de Jong, Wilfried W., Bloemendal, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22190/
https://ncbi.nlm.nih.gov/pubmed/10393950
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