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Resistance of Escherichia coli to penicillins: fine-structure mapping and dominance of chromosomal beta-lactamase mutations.

Seven Escherichia coli K-12 mutants with a lowered chromosomal beta-lactamase activity were analyzed genetically. The beta-lactamase-negative mutants isolated from ampA1-carrying strains (resistant to 10 microgram of ampicillin per ml) all carried genetic lesions very close to the ampA1 mutation, wh...

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Autores principales: Normark, S, Burman, L G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1977
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC221818/
https://ncbi.nlm.nih.gov/pubmed/334718
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