Striatal Proteomic Analysis Suggests that First L-Dopa Dose Equates to Chronic Exposure

L-3,4-dihydroxypheylalanine (L-dopa)-induced dyskinesia represent a debilitating complication of therapy for Parkinson's disease (PD) that result from a progressive sensitization through repeated L-dopa exposures. The MPTP macaque model was used to study the proteome in dopamine-depleted striat...

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Detalhes bibliográficos
Main Authors: Scholz, Birger, Svensson, Marcus, Alm, Henrik, Sköld, Karl, Fälth, Maria, Kultima, Kim, Guigoni, Céline, Doudnikoff, Evelyne, Li, Qin, Crossman, Alan R., Bezard, Erwan, Andrén, Per E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217596/
https://ncbi.nlm.nih.gov/pubmed/18270577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001589
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