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Barriers to antigenic escape by pathogens: trade-off between reproductive rate and antigenic mutability
BACKGROUND: A single measles vaccination provides lifelong protection. No antigenic variants that escape immunity have been observed. By contrast, influenza continually evolves new antigenic variants, and the vaccine has to be updated frequently with new strains. Both measles and influenza are RNA v...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2217548/ https://ncbi.nlm.nih.gov/pubmed/18005440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-229 |
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