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A Conducting State with Properties of a Slow Inactivated State in a Shaker K(+) Channel Mutant

In Shaker K(+) channel, the amino terminus deletion Δ6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Δ6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove slow inactivation, producing a noninactivating channel. However, despite the fact that...

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Bibliographische Detailangaben
Hauptverfasser: Olcese, Riccardo, Sigg, Daniel, Latorre, Ramon, Bezanilla, Francisco, Stefani, Enrico
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217242/
https://ncbi.nlm.nih.gov/pubmed/11158167
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