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Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation

UVB-induced DNA damage is a crucial event in UVB-mediated apoptosis. On the other hand, UVB directly activates death receptors on the cell surface including CD95, implying that UVB-induced apoptosis can be initiated at the cell membrane through death receptor clustering. This study was performed to...

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Main Authors: Kulms, Dagmar, Pöppelmann, Birgit, Yarosh, Daniel, Luger, Thomas A., Krutmann, Jean, Schwarz, Thomas
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22172/
https://ncbi.nlm.nih.gov/pubmed/10393932
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