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Mechanisms of Barbiturate Inhibition of Acetylcholine Receptor Channels

We used patch clamp techniques to study the inhibitory effects of pentobarbital and barbital on nicotinic acetylcholine receptor channels from BC3H-1 cells. Single channel recording from outside-out patches reveals that both drugs cause acetylcholine-activated channel events to occur in bursts. The...

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Detalhes bibliográficos
Main Authors: Dilger, James P., Boguslavsky, Rebecca, Barann, Martin, Katz, Tamir, Vidal, Ana Maria
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217072/
https://ncbi.nlm.nih.gov/pubmed/9089445
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