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Cyclic nucleotide-gated channels of rat olfactory receptor cells: divalent cations control the sensitivity to cAMP

cAMP-gated channels were studied in inside-out membrane patches excised from the apical cellular pole of isolated olfactory receptor cells of the rat. In the absence of divalent cations the dose-response curve of activation of patch current by cAMP had a KM of 4.0 microM at -50 mV and of 2.5 microM...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216850/
https://ncbi.nlm.nih.gov/pubmed/7513349
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