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Mechanism of 4-aminopyridine action on voltage-gated potassium channels in lymphocytes

The mechanism by which 4-aminopyridine (4-AP) blocks the delayed rectifier type potassium (K+) channels present on lipopolysaccharide- activated murine B lymphocytes was investigated using whole-cell and single channel patch-clamp recordings. 4-AP (1 microM-5 mM) was superfused for 3-4 min before ap...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216608/
https://ncbi.nlm.nih.gov/pubmed/1613484
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