Improved Long-Distance Polymerase Chain Reaction for the Detection of t(8;14)(q24;q32) in Burkitt’s Lymphomas

The t(8;14)(q24;q32), involving MYC gene (8q24) and the immunoglobulin heavy chain (IgH) locus (14q32), represents about 75% of all translocations in Burkitt’s lymphoma (BL). Due to the great variability of the breakpoint region, a standard polymerase chain reaction assay is not sufficient for the d...

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Bibliographic Details
Main Authors: Basso, Katia, Frascella, Emanuela, Zanesco, Luigi, Rosolen, Angelo
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
Subjects:
Technical Advances
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216451/
https://ncbi.nlm.nih.gov/pubmed/10550304
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