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Thiazide diuretics directly induce osteoblast differentiation and mineralized nodule formation by targeting a NaCl cotransporter in bone

Thiazide diuretics are used, worldwide, as the first-choice drug for patients with uncomplicated hypertension. In addition to their anti-hypertensive actions, they increase bone mineral density and reduce the prevalence of fractures, indicating that thiazides may have a role in the management of pos...

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Autors principals: Dvorak, Melita M, De Joussineau, Cyrille, Carter, D Howard, Pisitkun, Trairak, Knepper, Mark A, Gamba, Gerardo, Kemp, Paul J, Riccardi, Daniela
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216427/
https://ncbi.nlm.nih.gov/pubmed/17656470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030348
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