Functional Consequences of Toll-like Receptor 4 Polymorphisms

Toll-like receptor 4 (TLR4) is an important pathogen recognition receptor that recognizes mainly lipopolysaccharide (LPS) of Gram-negative bacteria, but also structures from fungal and mycobacterial pathogens, as well as endogenous ligands. Two nonsynonymous polymorphisms of TLR4, Asp299Gly and Thr3...

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Hlavní autoři: Ferwerda, Bart, McCall, Matthew BB, Verheijen, Karlijn, Kullberg, Bart-Jan, van der Ven, André JAM, Van der Meer, Jos WM, Netea, Mihai G
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2008
Témata:
Review Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215765/
https://ncbi.nlm.nih.gov/pubmed/18231573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00135.Ferwerda
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