Selective interaction of the C2 domains of phospholipase C-β(1) and -β(2) with activated Gα(q) subunits: An alternative function for C2-signaling modules

Phospholipase C (PLC)-β(1) and PLC-β(2) are regulated by the G(q) family of heterotrimeric G proteins and contain C2 domains. These domains are Ca(2+)-binding modules that serve as membrane-attachment motifs in a number of signal transduction proteins. To determine the role that C2 domains play in P...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wang, Tieli, Pentyala, Srinivas, Elliott, John T., Dowal, Louisa, Gupta, Ekta, Rebecchi, Mario J., Scarlata, Suzanne
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.7843
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