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IFN-γ Mediates the Rejection of Haematopoietic Stem Cells in IFN-γR1-Deficient Hosts

BACKGROUND: Interferon-γ receptor 1 (IFN-γR1) deficiency is a life-threatening inherited disorder, conferring predisposition to mycobacterial diseases. Haematopoietic stem cell transplantation (HSCT) is the only curative treatment available, but is hampered by a very high rate of graft rejection, ev...

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Detalhes bibliográficos
Main Authors: Rottman, Martin, Soudais, Claire, Vogt, Guillaume, Renia, Laurent, Emile, Jean-François, Decaluwe, Hélène, Gaillard, Jean-Louis, Casanova, Jean-Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214797/
https://ncbi.nlm.nih.gov/pubmed/18232731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050026
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