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The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity

Studies have shown that the immune system can recognize self-antigens under conditions (eg, cell injury) in which the self-tissue might elaborate immune-activating endogenous danger signals. Uric acid (UA) is an endogenous danger signal recently identified to be released from dying cells. Prior work...

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Detalhes bibliográficos
Main Authors: Behrens, Marshall D., Wagner, Wolfgang M., Krco, Christopher J., Erskine, Courtney L., Kalli, Kimberly R., Krempski, James, Gad, Ekram A., Disis, Mary L., Knutson, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214762/
https://ncbi.nlm.nih.gov/pubmed/18029553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-117184
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