The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6(−/−) mice

Platelet glycoprotein VI (GPVI) is a key receptor for collagens that mediates the propagation of platelet attachment and activation. Targeted disruption of the murine gene Gp6 on a mixed 129 × 1/SvJ × C57BL/6J background causes the expected defects in collagen-dependent platelet responses in vitro....

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Autors principals: Cheli, Yann, Jensen, Deborah, Marchese, Patrizia, Habart, David, Wiltshire, Tim, Cooke, Michael, Fernandez, José A., Ware, Jerry, Ruggeri, Zaverio M., Kunicki, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Hemostasis, Thrombosis, and Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214743/
https://ncbi.nlm.nih.gov/pubmed/17991808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111369
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