Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet α granules and differentially released

Platelets, in addition to their function in hemostasis, play an important role in wound healing and tumor growth. Because platelets contain angiogenesis stimulators and inhibitors, the mechanisms by which platelets regulate angiogenesis remain unclear. As platelets adhere to activated endothelium, t...

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Main Authors: Italiano, Joseph E., Richardson, Jennifer L., Patel-Hett, Sunita, Battinelli, Elisabeth, Zaslavsky, Alexander, Short, Sarah, Ryeom, Sandra, Folkman, Judah, Klement, Giannoula L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Hemostasis, Thrombosis, and Vascular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214735/
https://ncbi.nlm.nih.gov/pubmed/17962514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-113837
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