Prevalence of mutations associated with antimalarial drugs in Plasmodium falciparum isolates prior to the introduction of sulphadoxine-pyrimethamine as first-line treatment in Iran

BACKGROUND: This work was carried out to assess the patterns and prevalence of resistance to chloroquine (CQ) and sulphadoxine-pyrimethamine (SP) in Iran. METHODS: The prevalence of pfcrt K76T, pfmdr1 N86Y, pfdhfr N51I, C59R, S108N/T and I164L and codons S436F/A, A437G, K540E, A581E, and A613S/T in...

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Detalhes bibliográficos
Main Authors: Zakeri, Sedigheh, Afsharpad, Mandana, Raeisi, Ahmad, Djadid, Navid Dinparast
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214731/
https://ncbi.nlm.nih.gov/pubmed/17999755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-6-148
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