Protective immunity against murine hepatitis virus (MHV) induced by intranasal or subcutaneous administration of hybrids of tobacco mosaic virus that carries an MHV epitope

Hybrids of tobacco mosaic virus (TMV) were constructed with the use of fusion to the coat protein peptides of 10 or 15 amino acids, containing the 5B19 epitope from the spike protein of murine hepatitis virus (MHV) and giving rise to TMV-5B19 and TMV-5B19L, respectively. The TMV hybrids were propaga...

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Main Authors: Koo, Moses, Bendahmane, Mohammed, Lettieri, Gerard A., Paoletti, Alyssa D., Lane, Thomas E., Fitchen, John H., Buchmeier, Michael J., Beachy, Roger N.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22137/
https://ncbi.nlm.nih.gov/pubmed/10393897
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