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Isolation of anti-toxin single domain antibodies from a semi-synthetic spiny dogfish shark display library

BACKGROUND: Shark heavy chain antibody, also called new antigen receptor (NAR), consists of one single Variable domain (V(H)), containing only two complementarity-determining regions (CDRs). The antigen binding affinity and specificity are mainly determined by these two CDRs. The good solubility, ex...

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Bibliografische gegevens
Hoofdauteurs: Liu, Jinny L, Anderson, George P, Goldman, Ellen R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213646/
https://ncbi.nlm.nih.gov/pubmed/18021450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-78
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