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A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

The peripheral nuclear lamina, which is largely but not entirely associated with inactive chromatin, is considered to be an important determinant of nuclear structure and gene expression. We present here an inducible system to target a genetic locus to the nuclear lamina in living mammalian cells. U...

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Hlavní autoři: Kumaran, R. Ileng, Spector, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213611/
https://ncbi.nlm.nih.gov/pubmed/18195101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706060
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