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Locus-specific and activity-independent gene repositioning during early tumorigenesis

The mammalian genome is highly organized within the cell nucleus. The nuclear position of many genes and genomic regions changes during physiological processes such as proliferation, differentiation, and disease. It is unclear whether disease-associated positioning changes occur specifically or are...

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Detalhes bibliográficos
Main Authors: Meaburn, Karen J., Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213600/
https://ncbi.nlm.nih.gov/pubmed/18195100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708204
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