Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

Spine density in the hippocampus changes during the estrus cycle and is dependent on the activity of local aromatase, the final enzyme in estrogen synthesis. In view of the abundant gonadotropin-releasing hormone receptor (GnRH-R) messenger RNA expression in the hippocampus and the direct effect of...

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Bibliographic Details
Main Authors: Prange-Kiel, Janine, Jarry, Hubertus, Schoen, Michael, Kohlmann, Patrick, Lohse, Christina, Zhou, Lepu, Rune, Gabriele M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213593/
https://ncbi.nlm.nih.gov/pubmed/18227283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707043
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