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Functionally Inert HIV-Specific Cytotoxic T Lymphocytes Do Not Play a Major Role in Chronically Infected Adults and Children

The highly sensitive quantitation of virus-specific CD8(+) T cells using major histocompatibility complex–peptide tetramer assays has revealed higher levels of cytotoxic T lymphocytes (CTLs) in acute and chronic virus infections than were recognized previously. However, studies in lymphocytic chorio...

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Autors principals: Goulder, Philip J.R., Tang, Yanhua, Brander, Christian, Betts, Michael R., Altfeld, Marcus, Annamalai, Ken, Trocha, Alicja, He, Suqin, Rosenberg, Eric S., Ogg, Graham, O'Callaghan, Christopher A., Kalams, Spyros A., McKinney, Ross E., Mayer, Kenneth, Koup, Richard A., Pelton, Stephen I., Burchett, Sandra K., McIntosh, Kenneth, Walker, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213508/
https://ncbi.nlm.nih.gov/pubmed/11120778
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