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Pancreatic β Cell–specific Expression of  Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes

The cytotoxicity of reactive oxygen intermediates (ROIs) has been implicated in the destruction of pancreatic β cells in insulin-dependent diabetes mellitus (IDDM). Thioredoxin (TRX), a redox (reduction/oxidation)-active protein, has recently been shown to protect cells from oxidative stress and apo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hotta, Mizuo, Tashiro, Fumi, Ikegami, Hiroshi, Niwa, Hitoshi, Ogihara, Toshio, Yodoi, Junji, Miyazaki, Jun-ichi
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 1998
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213419/
https://ncbi.nlm.nih.gov/pubmed/9782121
תגים: הוספת תג
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