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Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

Lymphotoxin (LT)α knockout mice, as well as double LTα/tumor necrosis factor (TNF) knockout mice, show a severe splenic disorganization with nonsegregating T/B cell zones and complete absence of primary B cell follicles, follicular dendritic cell (FDC) networks, and germinal centers. In contrast, as...

詳細記述

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書誌詳細
主要な著者: Alexopoulou, Lena, Pasparakis, Manolis, Kollias, George
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213356/
https://ncbi.nlm.nih.gov/pubmed/9705956
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