MHC Class II Expression Restricted to CD8α(+) and CD11b(+) Dendritic Cells Is Sufficient for Control of Leishmania major

Control of the intracellular protozoan, Leishmania major, requires major histocompatibility complex class II (MHC II)–dependent antigen presentation and CD4(+) T cell T helper cell 1 (Th1) differentiation. MHC II–positive macrophages are a primary target of infection and a crucial effector cell cont...

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Bibliographic Details
Main Authors: Lemos, Maria P., Esquivel, Fatima, Scott, Phillip, Laufer, Terri M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213304/
https://ncbi.nlm.nih.gov/pubmed/14993255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030795
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