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Imaging the Single Cell Dynamics of CD4(+) T Cell Activation by Dendritic Cells in Lymph Nodes

The adaptive immune response is initiated in secondary lymphoid organs by contact between antigen-bearing dendritic cells (DCs) and antigen-specific CD4(+) T cells. However, there is scant information regarding the single cell dynamics of this process in vivo. Using two-photon microscopy, we imaged...

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Bibliographic Details
Main Authors: Miller, Mark J., Safrina, Olga, Parker, Ian, Cahalan, Michael D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213293/
https://ncbi.nlm.nih.gov/pubmed/15466619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041236
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