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Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
Stem cells reside in a specialized niche that regulates their abundance and fate. Components of the niche have generally been defined in terms of cells and signaling pathways. We define a role for a matrix glycoprotein, osteopontin (OPN), as a constraining factor on hematopoietic stem cells within t...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213260/ https://ncbi.nlm.nih.gov/pubmed/15928197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041992 |
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