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Interaction of CagA with Crk plays an important role in Helicobacter pylori–induced loss of gastric epithelial cell adhesion

CagA protein is a major virulence factor of Helicobacter pylori, which is delivered into gastric epithelial cells and elicits growth factor–like responses. Once within the cells, CagA is tyrosine phosphorylated by Src family kinases and targets host proteins required to induce the cell responses. We...

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Detalhes bibliográficos
Main Authors: Suzuki, Masato, Mimuro, Hitomi, Suzuki, Toshihiko, Park, Morag, Yamamoto, Tadashi, Sasakawa, Chihiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213224/
https://ncbi.nlm.nih.gov/pubmed/16275761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051027
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