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Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues

Expression of killer cell Ig-like receptors (KIRs) diversifies human natural killer cell populations and T cell subpopulations. Whereas the major histocompatibility complex class I binding functions of inhibitory KIR are known, specificities for the activating receptors have resisted analysis. To un...

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Autori principali: Abi-Rached, Laurent, Parham, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213150/
https://ncbi.nlm.nih.gov/pubmed/15837816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042558
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