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Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus

Rhinoviruses are the major trigger of acute asthma exacerbations and asthmatic subjects are more susceptible to these infections. To investigate the underlying mechanisms of this increased susceptibility, we examined virus replication and innate responses to rhinovirus (RV)-16 infection of primary b...

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Detalhes bibliográficos
Main Authors: Wark, Peter A.B., Johnston, Sebastian L., Bucchieri, Fabio, Powell, Robert, Puddicombe, Sarah, Laza-Stanca, Vasile, Holgate, Stephen T., Davies, Donna E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213100/
https://ncbi.nlm.nih.gov/pubmed/15781584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041901
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