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Humanized mice: are we there yet?

Animal models have been instrumental in increasing the understanding of human physiology, particularly immunity. However, these animal models have been limited by practical considerations and genetic diversity. The creation of humanized mice that carry partial or complete human physiological systems...

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Detalhes bibliográficos
Main Authors: Macchiarini, Francesca, Manz, Markus G., Palucka, A. Karolina, Shultz, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212979/
https://ncbi.nlm.nih.gov/pubmed/16301740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051547
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