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Eosinophil adhesion under flow conditions activates mechanosensitive signaling pathways in human endothelial cells

Leukocyte transmigration can be affected by shear stress; however, the mechanisms by which shear stress modulates transmigration are unknown. We found that adhesion of eosinophils or an eosinophilic cell line to intereukin 4–stimulated endothelial cells led to a shear-dependent increase in endotheli...

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Bibliographic Details
Main Authors: Cuvelier, Susan L., Paul, Smitha, Shariat, Neda, Colarusso, Pina, Patel, Kamala D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212932/
https://ncbi.nlm.nih.gov/pubmed/16172263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041315
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