Plasmacytoid predendritic cells initiate psoriasis through interferon-α production

Psoriasis is one of the most common T cell–mediated autoimmune diseases in humans. Although a role for the innate immune system in driving the autoimmune T cell cascade has been proposed, its nature remains elusive. We show that plasmacytoid predendritic cells (PDCs), the natural interferon (IFN)-α–...

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Detalhes bibliográficos
Main Authors: Nestle, Frank O., Conrad, Curdin, Tun-Kyi, Adrian, Homey, Bernhard, Gombert, Michael, Boyman, Onur, Burg, Günter, Liu, Yong-Jun, Gilliet, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212894/
https://ncbi.nlm.nih.gov/pubmed/15998792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050500
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