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Broadly targeted human cytomegalovirus-specific CD4(+) and CD8(+) T cells dominate the memory compartments of exposed subjects

Human cytomegalovirus (HCMV) infections of immunocompetent hosts are characterized by a dynamic, life-long interaction in which host immune responses, particularly of T cells, restrain viral replication and prevent disease but do not eliminate the virus or preclude transmission. Because HCMV is amon...

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Autori principali: Sylwester, Andrew W., Mitchell, Bridget L., Edgar, John B., Taormina, Cara, Pelte, Christian, Ruchti, Franziska, Sleath, Paul R., Grabstein, Kenneth H., Hosken, Nancy A., Kern, Florian, Nelson, Jay A., Picker, Louis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212883/
https://ncbi.nlm.nih.gov/pubmed/16147978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050882
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